Application
detects overexpressed human CTLA4 by western blot analysis.| Product Name | CTLA4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [8F16] to CTLA4This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant CTLA-4 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 8F16 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB(1:500-1000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CTLA4 CELIAC3 IDDM12 CTLA-4 GRD4 GSE CD CD152 cytotoxic T-lymphocyte-associated protein 4 |
|---|---|
| Target | CTLA4 |
| Tissue Specificity | This antibody was selected for its ability to detect human CTLA4 / CD152 |
Application
detects overexpressed human CTLA4 by western blot analysis.| Application Notes | WB(1:500-1000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
