| Product Name | CTLA4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [BNI3] to CTLA4CTLA4 has a critical role in T cell differentiation and contributes to the maintenance of peripheral T cell tolerance to self antigens. It exerts its major effects on T cell immune responses via regulation of the cell cycle and may be involved in T-cell activation. It binds to B7-1 (CD80) and B7-2 (CD86), and it contains 1 immunoglobulin-like V-type domain. Widely expressed with highest levels in lymphoid tissues. |
| Immunogen | Human CTLA-4/human IgG heavy chain fusion protein (CTLA-4/Ig). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | BNI3 |
| Host Species | Mouse |
| Tested Applications | FACSICC/IFIHC-F |
| FACS: Use 2μg for 10^5 cells. IF: Use 2μg for 10^5 cells. IHC-Fr: Use at a concentration of 5 - 50 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Gene Synonyms | 1493 CTLA-4 P16410 CD GSE CELIAC3 CTLA4 123890 CD152 CTLA 4 |
|---|---|
| Target | CTLA4 |
| Cellular Localization | Type I membrane protein. |
| Application Notes | FACS: Use 2μg for 10^5 cells. IF: Use 2μg for 10^5 cells. IHC-Fr: Use at a concentration of 5 - 50 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None. Constituents: PBS, 1mg/ml BSA. pH 7.2 |
