Rabbit polyclonal to CXCR6Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require co-receptors, in addition to CD4, to infect target cells. Some G-protein coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV co-receptors. An orphan G-protein coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV co-receptor (1-4). Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.
Immunogen
Synthetic peptide, corresponding to amino acids 319-338 of Human CXCR6.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blot at 1:1000.:
Species Reactivity
Human
Concentration
0.5mg/ml
Target Information
Gene Synonyms
CXCR6 TYMSTR 10663 STRL33 O00574 BONZO 605163
Target
CXCR6
Cellular Localization
Integral membrane protein
Application
Application
Western blot analysis of whole cell lysate from SW1353 chondrosarcoma cell line probed with Rabbit anti Human Bonzo
Positive Control
Whole cell lysate from SW1353 cells
Application Notes
Western blot at 1:1000.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C.