Application
WB analysis of A549, HepG2 and HeLa lysates using Cytochrome P450 17A1 antibody at a dilution of 1:1,000.| Product Name | CYP17A1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [6E1-H9-F6] to CYP17A1This gene encodes a member of the cytochrome P450 superfamily of enzymes.The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.This protein localizes to the endoplasmic reticulum.It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins,mineralocorticoids,glucocorticoids,androgens,and estrogens.Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency,17-alpha-hydroxylase/17,20-lyase deficiency,pseudohermaphroditism,and adrenal hyperplasia.[provided by RefSeq,Jul 2008] |
| Immunogen | Purified recombinant human CYP17A1 protein fragments expressed in E.coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 6E1-H9-F6 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | cytochrome P450 family 17 subfamily A polypeptide 1 CYP17A1 P450C17 CPT7 S17AH CYP17 |
|---|---|
| Target | CYP17A1 |
| Molecular Weight(MW) | 60kDa (note) |
| Cellular Localization | Membrane. |
Application
WB analysis of A549, HepG2 and HeLa lysates using Cytochrome P450 17A1 antibody at a dilution of 1:1,000.| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Ascites |
