| Product Name | Cystatin B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3F13] to Cystatin BThe cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant Cystatin-B |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 3F13 |
| Host Species | Mouse |
| Tested Applications | NeutWB |
| WB(1:500-1000)|Neutralization of Cystatin-B: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CST6 ULD STFB PME cystatin B (stefin B) CSTB EPM1A EPM1 |
|---|---|
| Target | Cystatin B |
| Tissue Specificity | This antibody was selected for its ability to detect human Cystatin-B. |
| Application Notes | WB(1:500-1000)|Neutralization of Cystatin-B: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
