Application
Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with DDB1 antibody at 1:500 followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Product Name | DDB1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to DDB1This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq] |
| Immunogen | Synthetic peptide - KLH conjugated |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| WB (1:500 - 1:1000), IP, ELISA (1:2000 - 1:10000), IHC-P (1:500): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DDBA UV-DDB1 XAP1 XPCE XPE XPE-BF XPE BF UV DDB1 XPEBF UVDDB1 |
|---|---|
| Tissue Specificity | Amino acids 198-213 of Human DDB1 (internal) coupled to KLH. |
Application
Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with DDB1 antibody at 1:500 followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Application Notes | WB (1:500 - 1:1000), IP, ELISA (1:2000 - 1:10000), IHC-P (1:500): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Storage Buffer | 0.01% sodium azide. |
