Rabbit polyclonal to Desmin (prediluted)Desmin is an intermediate filament protein of both smooth and striated muscles. Antibody to desmin reacts with striated (skeletal and cardiac) as well as smooth muscle cells. In skeletal and cardiac muscles, the staining is confined to the Z-bands giving a characteristic striated appearance. Antidesmin antibody is useful in identification of tumours of myogenic origin.
Immunogen
Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
For IHC-P: Use at neat dilution for 10 min at RT. No special pretreatment is required. Optimal dilutions/concentrations should be determined by the researcher.
Human Skeletal Muscle stained with anti-Desmin antibody
Application
staining Desmin in human leiomyosarcoma by Immunohistochemistry (FFPE-sections).
Positive Control
Muscle, Sarcoma
Application Notes
For IHC-P: Use at neat dilution for 10 min at RT. No special pretreatment is required. Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution and store at 4°C. Do not freeze.