Mouse monoclonal [D33] to Desmin predilutedThis gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq]
Immunogen
From human muscle.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
D33
Host Species
Mouse
Tested Applications
IHC-P
For IHC-P: Ready-to-use, we suggest an incubation period of 30 min at RT. Prolonged fixation in formalin might destroy the antigen and hence the staining. Optimal dilutions/concentration should be determined by the researcher.
This antibody reacts with desmin protein of 53 kD. Both striated as well as smooth muscle cells stain well with this antibody.
Cellular Localization
Cytoplasmic
Light Chain Type
kappa
Application
Application
IHC-P analysis of human leiomyoma using Desmin antibody [D33].
Application
Formalin fixed paraffin embedded human leiomyoma stained with Desmin antibody .
Positive Control
Leiomyoma
Application Notes
For IHC-P: Ready-to-use, we suggest an incubation period of 30 min at RT. Prolonged fixation in formalin might destroy the antigen and hence the staining. Optimal dilutions/concentration should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.