| Product Name | Desmoglein 3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4W25] to Desmoglein 3Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant Desmoglein 3. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4W25 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| WB(1:500-1000)|IHC (paraffin)(1:20-100): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CDHF6 desmoglein 3 PVA DSG3 |
|---|---|
| Target | Desmoglein 3 |
| Tissue Specificity | This antibody was selected for its ability to detect human Desmoglein 3. |
| Application Notes | WB(1:500-1000)|IHC (paraffin)(1:20-100): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
