| Product Name | E2F1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [KH20] to E2F1E2F's are DNA binding proteins that associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. E2F 1 also requires DP 1 for efficient DNA binding and transcription modification. E2F 1 is proposed to be involved in several cellular processes that range from tumor suppression, cell cycle progression, and oncogenesis. E2F 1 overexpression can also drive cells into apoptosis. These observations place E2F among a group of apoptosis inducers that includes; c Myc, adenovirus E1A, and the human papilloma virus E7protein. |
| Immunogen | Recombinant full length protein (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | KH20 |
| Host Species | Mouse |
| Tested Applications | ICC/IF |
| For IF: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.2mg/ml |
| Purification | Protein A |
| Gene Synonyms | E2F1 E2F-1 Q01094 189971 1869 RBP3 RBBP3 E2F 1 |
|---|---|
| Target | E2F1 |
| Cellular Localization | Nuclear |
| Light Chain Type | kappa |
| Positive Control | MAD109 and HL-60 cells. |
|---|---|
| Application Notes | For IF: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide |
