Application
Western blot analysis using anti-EP300 monoclonal antibody against truncated EP300-His recombinant protein(1).| Product Name | EP300 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [7D8A6] to EP300This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008] |
| Immunogen | The immunogen corresponding to EP300 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 7D8A6 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KAT3B P300 RSTS2 |
|---|---|
| Target | EP300 |
| Cellular Localization | In the presence of ALX1 relocalizes from the cytoplasm to the nucleus. |
Application
Western blot analysis using anti-EP300 monoclonal antibody against truncated EP300-His recombinant protein(1).| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
