Mouse monoclonal antibody [10D2] to ETS1This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Immunogen
The immunogen corresponding to human ETS1 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10D2
Host Species
Mouse
Tested Applications
ELISAIHCIHC-PWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
EWSR2 ETS-1
Target
ETS1
Molecular Weight(MW)
50.4 kDa (note)
Application
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue(A) and breast tumor(B) uing ETS1 mAb.
Application
Western blot analysis using ETS1 mAb against Jurkat (1), HepG2 (2) and ETS1-hIgGFc transfected HEK293 (3)cell lysate.
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.