Mouse monoclonal antibody [4A9D6] to FAKThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010]
Immunogen
The immunogen corresponding to FAK expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Clone Number
4A9D6
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
PP125FAK FADK PTK2 P125FAK PPP1R71 FRNK FAK1
Target
FAK
Cellular Localization
Constituent of focal adhesions.
Application
Application
Western blot analysis using anti-human FAK monoclonal antiobdy against truncated FAK recombinant protein.
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.