| Product Name | FANCJ antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody to Brip1 / FANCJ (Similar to BRCA1-binding helicase-like protein BACH1) (clone GO11-3E6)BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation. (1-4) |
| Immunogen | Fusion protein 647-1043 of human Brip1. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | GO11-3E6 |
| Host Species | Mouse |
| Tested Applications | WB |
| By Western blot, this nuclear protein antibody recognizes a band at 130 kDa, representing Brip1. This antibody does not work in immunofluorescence.Suggested working dilutions: *Western Blot - 1:500 Immunoprecipitation - NDImmunohistochemistry - ND*The investigator should determine the optimal working dilution for a specific application.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FANCJ 114480 BACH1 83990 MGC126521 FLJ90232 BRIP1 OF Q9BX63 MGC126523 |
|---|---|
| Target | BRIP1 |
| Tissue Specificity | This antibody is specific for Brip1. |
| Positive Control | HeLa whole and nuclear extracts, Raji whole cell extracts. |
|---|---|
| Application Notes | By Western blot, this nuclear protein antibody recognizes a band at 130 kDa, representing Brip1. This antibody does not work in immunofluorescence.Suggested working dilutions: *Western Blot - 1:500 Immunoprecipitation - NDImmunohistochemistry - ND*The investigator should determine the optimal working dilution for a specific application.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4 degrees Celcius. For long-term storage, store at -20 degrees Celcius. |
| Storage Buffer | 0.1 ml of mouse ascites (16.3 mg/ml) with Sodium Azide. |
