Application
Western bot of HeLa lysate showing specific immunolabeling of the ~34k Fibrillarin protein using Fibrillarin antibody [38F3] .| Product Name | Fibrillarin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [38F3] to FibrillarinInvolved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Involved in the biogenesis of the 18S rRNA. |
| Immunogen | Yeast nuclear preparations |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 38F3 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| Optimal working dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Gene Synonyms | fibrillarin NOP1 RNU3IP1 FLRN FIB FBL |
|---|---|
| Target | Fibrillarin |
| Molecular Weight(MW) | 34 (note) |
| Cellular Localization | Fibrillar region of the nucleolus. |
Application
Western bot of HeLa lysate showing specific immunolabeling of the ~34k Fibrillarin protein using Fibrillarin antibody [38F3] .| Application Notes | Optimal working dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | total IgG fraction + 10 mM NaN3. |
