Application
Immunofluorescence of FKBP12 in A431 cells with FKBP12 antibody at 20 ug/mL.Application
Western blot analysis of FKBP12 in A431 cell lysate with FKBP12 antibody at 1 ug/ml.Application
Immunocytochemistry of FKBP12 in A431 cells with FKBP12 antibody at 5 ug/mL.| Product Name | FKBP12 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to FKBP12The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008] |
| Immunogen | FKBP12 antibody was raised against an 18 amino acid peptide near the center of human FKBP12. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| IF: 20 ug/mL: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | FK506 binding protein 1A 12kDa FKBP-12 PKC12 PKCI2 FKBP1 FKBP1A PPIASE FKBP-1A |
|---|---|
| Target | FKBP12 |
| Tissue Specificity | FKBP12 antibody is human reactive. |
Application
Immunofluorescence of FKBP12 in A431 cells with FKBP12 antibody at 20 ug/mL.
Application
Western blot analysis of FKBP12 in A431 cell lysate with FKBP12 antibody at 1 ug/ml.
Application
Immunocytochemistry of FKBP12 in A431 cells with FKBP12 antibody at 5 ug/mL.| Application Notes | IF: 20 ug/mL: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
