Mouse Monoclonal antibody [A42] to FXR2FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. It may self-associate or interact with FMRP and FXR1. Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
Immunogen
His6-FXR2s fusion protein produced in a bacterial pET system
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
A42
Host Species
Mouse
Tested Applications
ELISAICC/IFIPWB
Optimal dilutions should be determined experimentally by the researcher.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Synonyms
9513 605339 FMR1L2 FXR2 P51116
Target
FXR2
Tissue Specificity
Human FXR2. Detects a band of approximately 92 kDa
Application Notes
Optimal dilutions should be determined experimentally by the researcher.:
Additional Information
Form
Liquid
Storage Instructions
Store at 2-8°C. For extended storage, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles.