| Product Name | Heme Oxygenase 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [GTS - 1] to Heme Oxygenase 1Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO1 and a constitutively expressed HO2. HO1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant. |
| Immunogen | Rat heme oxygenase 1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | GTS-1 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-FIHC-PInhibitionWB |
| For ELISA: Use at a dilution of 1:10,000 with solid phase antigen. For IHC-Fr: Use at a concentratio of 5-10 μg/ml. For IHC-P: Use at a concentration of 5-10 μg/ml. For WB: Use at a concentration of 5-10 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Heme Oxygenase 1 Ho1 Heox 141250 hsp32 24451 3162 Heme Oxygenase1 P09601 Hmox1 Hmox HO-1 bK286B10 HEOXG HO 1 |
|---|---|
| Target | Heme Oxygenase 1 |
| Tissue Specificity | reacts with human, rat and mouse heme oxygenase 1. It does not react with rabbit heme oxygenase 1 or heme oxygenase 2. This antibody will inhibit the activity of human or rat heme oxygenase 1. |
| Cellular Localization | Microsomal |
| Application Notes | For ELISA: Use at a dilution of 1:10,000 with solid phase antigen. For IHC-Fr: Use at a concentratio of 5-10 μg/ml. For IHC-P: Use at a concentration of 5-10 μg/ml. For WB: Use at a concentration of 5-10 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | 10mM Phosphate buffered saline, pH 7.4, containing 1% BSA |
