Rabbit Polyclonal antibody to Histone H3T11ph (phospho Thr11)Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]
Immunogen
A phospho specific peptide corresponding to residues surrounding T11 of human HIST1H3J
Modification
p-Thr11
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:2000:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
histone cluster 1 H3j HIST1H3J H3FJ H3/j
Target
Histone H3T11ph (phospho Thr11)
Molecular Weight(MW)
17 kDa (note)
Application
Application
WB analysis of extracts from untreated and EGF-treated U87 cells using Histone H3T11ph (phospho Thr11) antibody.
Application Notes
WB: 1:500 - 1:2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.