Western blot analysis using IKBKE monoclonal antiobdy against truncated IKBKE recombinant protein(1) and full-length IKBKE(aa1-716)-hIgGFc transfected COS7 cell lysate(2).
Mouse monoclonal antibody [6B4B5] to IKBKEIKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]
Immunogen
The immunogen corresponding to a region within amino acids 1 and 257 of IKBKE expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6B4B5
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
IKK-E IKKE IKK-I IKKI
Target
IKBKE
Cellular Localization
Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent.
Application
Application
Western blot analysis using IKBKE monoclonal antiobdy against truncated IKBKE recombinant protein(1) and full-length IKBKE(aa1-716)-hIgGFc transfected COS7 cell lysate(2).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.