Mouse monoclonal antibody ["1F3B3,3A6F11"] to IL1 alphaThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human IL1a expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
1F3B3,3A6F11
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
IL1 IL-1A IL1F1 IL1A IL1-ALPHA
Target
IL1 alpha
Molecular Weight(MW)
30.6 kDa (note)
Cellular Localization
The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Application
Application
Western blot analysis using IL1a mouse mAb against truncated IL1a recombinant protein.
Application
Western blot analysis using anti-IL1a monoclonal antiobdy against truncated IL1a recombinant protein.
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.