Application
ELISA analysis of pig IL-12 and human IL-12 protein(3ug/ml) using IL12 antibody.| Product Name | IL12 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [I-1A4] to IL12This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant human IL12 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | I-1A4 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-F |
| ELISA: Max Dilution 1/1000 as detecting antibody Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | HumanPig |
| Concentration | 1mg/ml |
| Gene Synonyms | IL-12B interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte maturation factor 2 p40) CLMF2 NKSF CLMF IL12B NKSF2 |
|---|---|
| Target | IL12 |
| Tissue Specificity | This antibody reacts with both stimulated and unstimulated monocytes in immunohistology. |
Application
ELISA analysis of pig IL-12 and human IL-12 protein(3ug/ml) using IL12 antibody.| Application Notes | ELISA: Max Dilution 1/1000 as detecting antibody Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
