| Product Name | IL3 Receptor alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [11A23] to IL-3R alphaThe protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012] |
| Immunogen | Human recombinant IL-3R alpha EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 11A23 |
| Host Species | Mouse |
| Tested Applications | IHCNeutWB |
| WB(1:500-1000)|IHC (frozen)(1:20-200)|Neutralization of IL-3R alpha mediated signaling: |
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | hIL-3Ra IL3RA IL3RAY IL3R interleukin 3 receptor alpha (low affinity) IL3RY IL3RX CD123 |
|---|---|
| Target | IL-3R alpha |
| Tissue Specificity | This antibody was selected for its ability to detect human IL-3R alpha. |
| Application Notes | WB(1:500-1000)|IHC (frozen)(1:20-200)|Neutralization of IL-3R alpha mediated signaling: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
