| Product Name | Integrin alpha 3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [IA3] to Integrin alpha 3Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 (VLA3), very common antigen 2 (VCA2), extracellular matrix receptor 1 (ECMR1), and galactoprotein b3 (GAPB3). |
| Immunogen | Cell preparation: Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | IA3 |
| Host Species | Mouse |
| Tested Applications | IHC-F |
| FuncS: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | VLA3 Very Late Activation Protein3 Receptor Alpha3 Subunit CD49c ITGA3 Integrin alpha 3 Integrin alpha3 Very Late Activation Protein 3 Receptor Alpha 3 Subunit galactoprotein B3 URO1 GAPB3 FLJ34631 FLJ34704 GAP-B3 MSK18 VCA-2 VL3A VLA3a VC |
|---|---|
| Target | Integrin alpha 3 |
| Tissue Specificity | Specific to alpha 3 integrin. IA3 is useful for studies on inhibition of cell-cell adhesion and cell-substrate adhesion. |
| Cellular Localization | Cell Membrane |
| Application Notes | FuncS: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline |
