| Product Name | K-Ras antibody [4F3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4F3] to K-RasThis gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] |
| Immunogen | KRAS (NP_004976, 16 a.a. ~ 126 a.a) partial recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 4F3 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| For ELISA (tested against immunogen): Use at an assay dependent dilution. For WB (tested against immunogen): Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanCat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | C-K-RAS , NS , KRAS1 , K-RAS4A , KRAS , KI-RAS , KRAS2 , K-RAS2B , NS3 , K-RAS2A , K-RAS4B , RASK2 |
|---|---|
| Tissue Specificity | This antibody may cross react with N-Ras and H-Ras proteins. |
| Positive Control | Recombinant protein |
|---|---|
| Application Notes | For ELISA (tested against immunogen): Use at an assay dependent dilution. For WB (tested against immunogen): Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2, containing no preservatives |
