| Product Name | Lck antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to LckLck (p56lck), a member of the Src family of non-receptor tyrosine protein kinases, is expressed predominantly in T cells. Lck function is critical both for T cell development in the thymus and activation of mature T cells in the periphery by antigen. The activity of Lck is known to be regulated by phosphorylation of two conserved tyrosine residues, Tyr-505 (equivalent to Tyr-529 in c-Src) and Tyr-394 (equivalent to Tyr-418 in c-Src). |
| Immunogen | Synthetic peptide (Human) derived from amino acid region 38 to 54 of Lck protein (based on Swiss Protein database, accession number P06239). The sequence is conserved in human and mouse. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB: Use at a concentration of 0.1 - 1.0 μg/ml. Predicted molecular weight: 60 kDa. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | LSK YT16 p56lck pp58lck |
|---|---|
| Target | Lck |
| Tissue Specificity | This antibody is useful to determine total levels of Lck protein. |
| Cellular Localization | Cytoplasmic |
| Positive Control | Full length untagged recombinant human Lck protein |
|---|---|
| Application Notes | For WB: Use at a concentration of 0.1 - 1.0 μg/ml. Predicted molecular weight: 60 kDa. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS pH 7.3 (without Mg2+ and Ca2+) containing 50% glycerol, 1.0mg/ml BSA (IgG, protease free). and 0.05% sodium azide. |
