Application
Immunohistochemistry: Metabotropic Glutamate Receptor 2 Antibody [ - Cells expressing vector only -immunostained with target antibodyApplication
Immunohistochemistry: mGluR2 antibody [ - Staining of untransfected (A) or mGluR2-transfected cells (B).| Product Name | mGluR2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Metabotropic Glutamate receptor 2The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. ESTs have been isolated from brain and testis libraries. Caution: GLUR2 refers to Ionotropic Glutamate Receptor 2, not to Metabotropic Glutamate Receptor 2 (mGLUR2). |
| Immunogen | Synthetic peptide [KLH conjugated] made to the 2nd extracellular loop |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-FIHC-PWB |
| We recommend the following starting dilutions: immunohistochemistry 4-8 ug/ml, Western Blot assay dependent, Immunocytochemistry assay dependent, Immunohistochemistry-Paraffin 4-8 ug/ml, Immunohistochemistry-Frozen 4-8 ug/ml. Optimal concentration should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Metabotropic Glutamate receptor2 HBGR2 GLUR 2 GluR K2 GRM2 Glutamate receptor2 precursor GluR B ionotropic GLURB AMPA selective glutamate receptor2 AMPA selective glutamate receptor 2 Glutamate receptor 2 precursor AMPA 2 AMPA2 glutamate rece |
|---|---|
| Target | Metabotropic Glutamate receptor 2 |
| Tissue Specificity | Metabotropic Glutamate Receptor 2 |
Application
Immunohistochemistry: Metabotropic Glutamate Receptor 2 Antibody [ - Cells expressing vector only -immunostained with target antibody
Application
Immunohistochemistry: mGluR2 antibody [ - Staining of untransfected (A) or mGluR2-transfected cells (B).| Application Notes | We recommend the following starting dilutions: immunohistochemistry 4-8 ug/ml, Western Blot assay dependent, Immunocytochemistry assay dependent, Immunohistochemistry-Paraffin 4-8 ug/ml, Immunohistochemistry-Frozen 4-8 ug/ml. Optimal concentration should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, PH 7.7 |
