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MRI1 antibody [9H7]

Catalog Number:OM263835
OM263835
Discount Price
OM263835-100ul
1~2 Week
100ul
OM263835-50ul
50ul
1~2 Week
Product Profile
Product Name MRI1 antibody [9H7]
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [9H7] to MRI1Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
Immunogen Protein expressed in 293T cell transfected with human MRI1 expression vector
Key Feature
Clonality Monoclonal
Isotype IgG2
Clone Number 9H7
Host Species Mouse
Tested Applications FACSICC/IFIHCIHC-PWB
Optimal working dilutions should be determined experimentally by the end user.

Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms Ypr118w, MRI1, MGC3207, MTNA
Target MRI1
Tissue Specificity is specific for human MRI1.
Cellular Localization Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
Application

Application

Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-MRI1mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas tissue using anti-MRI1mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-MRI1mouse monoclonal antibody. ( Dilution 1:50)

Application

Anti-MRI1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected with MRI1

Application

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-MRI1 mouse monoclonal antibody. ( Dilution 1:50)

Application

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MRI1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MRI1.
Application Notes Optimal working dilutions should be determined experimentally by the end user.

Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
Storage Buffer PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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