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MSH6 antibody

Catalog Number:OM263979
OM263979
Discount Price
OM263979-100ul
1~2 Week
100ul
OM263979-50ul
50ul
1~2 Week
Product Profile
Product Name MSH6 antibody
Antibody Type Primary Antibodies
Product description Mouse Monoclonal Antibody [5B11] to MSH6This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to human MSH6 expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 5B11
Host Species Mouse
Tested Applications ELISAWB
ELISA: 1/10000.:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms HSAP
GTBP
HNPCC5
Target MSH6
Molecular Weight(MW) 160 kDa (note)
Application

Application

ELISA analysis of control antigen and antigen using MSH6 antibody [5B11].

Application

WB analysis of (1) MCF-7, (2) HEK293 and (3) HCT116 lysates using MSH6 antibody [5B11].

Application

WB analysis of human MSH6 (a.a. 217-395) recombinant protein using MSH6 antibody [5B11].
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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