| Product Name | NALP1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [Nalpy1 - 4] to NALP1This gene encodes a member of the Ced 4 family of apoptosis proteins. Ced family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N terminal pyrin like motif, which is possibly involved in protein protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for NALP1, but the biological validity of some variants has not been determined. |
| Immunogen | Recombinant full length NALP1 (pyrin domain) (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | Nalpy1-4 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-PIPWB |
| ICC: Use at a dilution of 1/1000. IHC-Fr: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/1000. Predicted molecular weight: 171 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | 606636 22861 CARD7 NALP1 Q9C000 KIAA0926 PP1044 DKFZp586O1822 DEFCAP DEFCAPL/S DEFCAP-L/S DEFCAP L/S |
|---|---|
| Target | NALP1 |
| Cellular Localization | Cytoplasmic |
| Application Notes | ICC: Use at a dilution of 1/1000. IHC-Fr: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/1000. Predicted molecular weight: 171 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Sodium Azide; Constituents: PBS |
