| Product Name | Neuregulin-1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [19R23] to Neuregulin-1The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq, May 2009] |
| Immunogen | Recombinant Human NRG1 beta-1/HRG1 beta-1 EFG Domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 19R23 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| WB(1:500-1000)|ELISA(1:1000-2000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HRG NRG1 GGF2 HGL GGF MST131 NDF neuregulin 1 HRGA HRG1 SMDF ARIA |
|---|---|
| Target | Neuregulin-1 |
| Tissue Specificity | This antibody recognizes human Neuregulin EFG domain by ELISA and WB. |
| Application Notes | WB(1:500-1000)|ELISA(1:1000-2000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
