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NQO1 antibody

Catalog Number:OM265889
OM265889
Discount Price
OM265889-100ul
1~2 Week
100ul
OM265889-50ul
50ul
1~2 Week
Product Profile
Product Name NQO1 antibody
Antibody Type Primary Antibodies
Product description Mouse Monoclonal Antibody [4D12] to NQO1This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to human NQO1 expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 4D12
Host Species Mouse
Tested Applications ELISAFACSIHCIHC-PWB
ELISA: 1/10000.:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms DIA4
QR1
NMOR1
NMORI
DHQU
DTD
Target NQO1
Molecular Weight(MW) 31 kDa (note)
Application

Application

ELISA analysis of control antigen and antigen using NQO1 antibody [4D12].

Application

FACS analysis of NIH3T3 cells using NQO1 antibody [4D12] (green) or a negative control (red).

Application

IHC-P analysis of ovarian cancer tissues using NQO1 antibody [4D12].

Application

IHC-P analysis of testis tissues using NQO1 antibody [4D12].

Application

WB analysis of (1) A549, (2) SKNES, (3) HepG2, (4) MCF-7 and (5) HeLa lysates using NQO1 antibody [4D12].

Application

WB analysis of human NQO1 (a.a. 134-274) recombinant protein using NQO1 antibody [4D12].
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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