Application
WB analysis of extracts from various cells using Optineurin antibody.Application
IHC-P analysis of human esophageal cancer using Optineurin antibody at a dilution of 1:100.Application
IHC-P analysis of rat kidney using Optineurin antibody at a dilution of 1:100.| Product Name | Optineurin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to OptineurinThis gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human OPTN |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HIP7 FIP2 TFIIIA-INTP GLC1E ALS12 optineurin OPTN NRP HYPL |
|---|---|
| Target | Optineurin |
| Molecular Weight(MW) | 66 kDa (note) |
Application
WB analysis of extracts from various cells using Optineurin antibody.
Application
IHC-P analysis of human esophageal cancer using Optineurin antibody at a dilution of 1:100.
Application
IHC-P analysis of rat kidney using Optineurin antibody at a dilution of 1:100.| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
