Mouse monoclonal antibody [3D8] to CDKN1BThis gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human CDKN1B expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3D8
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
MEN1B KIP1 CDKN4 MEN4 P27KIP1
Target
CDKN1B
Molecular Weight(MW)
22 kDa (note)
Application
Application
Western blot analysis using CDKN1B mAb against CDKN1B-hIgGFc transfected HEK293 cell lysate.
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.