| Product Name | PAI-1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [12V3] to PAI-1This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| Immunogen | Human recombinant Serpin-E1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 12V3 |
| Host Species | Mouse |
| Tested Applications | NeutWB |
| WB(1:500-1000)|Neutralization of Serpin E1 bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PAI PLANH1 serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 PAI-1 PAI1 SERPINE1 |
|---|---|
| Target | PAI-1 |
| Tissue Specificity | This antibody was selected for its ability to specifically detect human Serpin-E1 |
| Application Notes | WB(1:500-1000)|Neutralization of Serpin E1 bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
