| Product Name | PAK6 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Polyclonal Anti - PAK6PAK6, a novel AR-interacting protein, shares a high degree of sequence similarity with p21-activated kinases. PAK6 cotranslocates into the nucleus with AR in response to androgen. In addition, AR and ERalpha transcriptional activites were inhibited by PAK6 in transient transfections with episomal and integrated reporter genes. PAK, which is highly expressed in testis and prostate tissues, could contribute to the effects of tamoxifen in breast cancer and in other tissues. |
| Immunogen | Amino acid 151-250 fragment from human PAK6. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IPWB |
| IP:1:100~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PAK5 |
|---|---|
| Target | PAK6 |
| Tissue Specificity | This antibody is specific for PAK6. |
| Positive Control | PC3 or ARCAP cell lines (human prostate cancer cell Lines) and bovine brain |
|---|---|
| Application Notes | IP:1:100~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, keep at -20 °C. Avoid repeated freeze thaw cycles. |
| Storage Buffer | 100 ul of affinity purified rabbit antisera with 0.05% sodium azide. |
