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PDX1 antibody, N-term

Catalog Number:OM268038
OM268038
Discount Price
OM268038-100ul
1~2 Week
100ul
OM268038-50ul
50ul
OM268038-20ul
20ul
1~2 Week
Product Profile
Product Name PDX1 antibody, N-term
Antibody Type Primary Antibodies
Product description Rabbit polyclonal to PDX1 (N-term)The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq]
Immunogen KLH conjugated synthetic peptide between 47~77 amino acids from the N-terminal region of human PDX1.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-PWB
ELISA: Use at 1:1,000:
Species Reactivity Human
Concentration 0.2mg/ml
Purification Affinity purified
Target Information
Gene Synonyms Glucosesensitive factor
IPF1
Islet/duodenum homeobox-1
IUF1
Insulin upstream factor 1
IDX1
Pancreas/duodenum hom
Insulin upstream factor1
STF-1
IUF-1
Islet/duodenum homeobox1
Somatostatintransactivating factor 1
IDX-1
Insulin promoter factor1
Target PDX1
Molecular Weight(MW) 30.771 kDa (note)
Application

Application

Formalin-fixed and paraffin-embedded human testis tissue reacted with PDX1 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

Western blot analysis of PDX1 (arrow) using rabbit polyclonal PDX1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDX1 gene (Lane 2)
Application Notes ELISA: Use at 1:1,000:
Additional Information
Form Liquid
Storage Instructions Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.09% (W/V) sodium azide
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