| Product Name | PGP9.5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [10A1] to human PGP 9.5UCHL1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons (Doran et al., 1983 [PubMed 6343558]).[supplied by OMIM] |
| Immunogen | Recombinant fusion protein corresponding to the full length of human PGP9.5. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 10A1 |
| Host Species | Mouse |
| Tested Applications | IHC-FIHC-PWB |
| For IHC-Fr: Use at a dilution of 1:20-1:40. For IHC-P: Use at a dilution of 1:20-1:40. GTX75786 requires antigen retrieval using heat treatment prior to staining of paraffin sections. For WB: Use at a dilution of 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PARK5 PGP 9.5 PGP9.5 PGP95 Uch-L1 Uch L1 UchL1 |
|---|---|
| Target | PGP9.5 |
| Tissue Specificity | recognises protein gene product 9.5 (PGP9.5), a ubiquitin hydrolase which is widely expressed in neuronal tissues. PGP9.5, also known as ubiquitin C-terminal hydrolase 1 (UCHL-1), has also been identified as a constituent of Lewy bodies. |
| Positive Control | Small intestine |
|---|---|
| Application Notes | For IHC-Fr: Use at a dilution of 1:20-1:40. For IHC-P: Use at a dilution of 1:20-1:40. GTX75786 requires antigen retrieval using heat treatment prior to staining of paraffin sections. For WB: Use at a dilution of 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Reconstitute with 1.0 ml dH2O. Buffer contains 0.09% sodium azide |
