| Product Name | PI3 kinase p85 alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [U13] to PI3 kinase p85 alphaPhosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | U13 |
| Host Species | Mouse |
| Tested Applications | IPWB |
| Immunoprecipitation: Max Dilution Neat: |
|
| Species Reactivity | HumanMouseMonkeyRatBovine |
| Concentration | 1mg/ml |
| Gene Synonyms | P85-ALPHA PIK3R1 P85 GRB1 |
|---|---|
| Target | PI 3 Kinase p85 alpha |
| Tissue Specificity | This antibody recognizes only those isoforms containing the SH3 domain (isoforms 1 and 4) but not those lacking the domain (isoforms 2,3 and 5). |
| Application Notes | Immunoprecipitation: Max Dilution Neat: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | 0.09%Sodium Azide |
