Application
Immunohistochemistry staining of AKT2 in breast tissue using AKT2 Antibody.Application
Immunohistochemistry staining of AKT2 in kidney using AKT2 Antibody.| Product Name | AKT2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AKT2, PKB beta, PKBBETA, PRKBB, Protein kinase Akt-2, Protein kinase B beta, RAC-PK-beta, Rac protein kinase beta, RAC-BETA, HIHGHH, PKBB |
| Product description | AKT2 encodes a RAC/AKT-type protein kinase that contains a N-terminal pleckstrin-homology (PH) domain and a central catalytic domain closely related to both cAMP-dependent protein kinase and protein kinase C. The protein is a member of PI3K-mediated signalling pathways associated with the regulation of proliferation, survival, protein synthesis, and metabolism. It is activated by a variety of growth factors. AKT2 has been shown to be transcriptionally regulated by MyoD and to activate MyoD-myocyte enhancer binding factor-2 (MEF2) transactivation activity during muscle differentiation. Glycogen synthase kinase 3 (GSK-3) also has been shown to be a downstream target of AKT2. The AKT2 gene is one of the human homologues of v-akt, the transduced oncogene of the AKT8 virus, which induces lymphomas in mice. It has been implicated in breast, ovarian, and pancreatic cancers. |
| Immunogen | AKT2 antibody was raised against a peptide corresponding to the C-Terminus of AKT2 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHCIPWB |
| AKT2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Gene Symbol | AKT2 |
|---|---|
| Alternative Names | AKT2 PKB beta PKBBETA PRKBB Protein kinase Akt-2 Protein kinase B beta RAC-PK-beta Rac protein kinase beta RAC-BETA HIHGHH PKBB |
Application
Immunohistochemistry staining of AKT2 in breast tissue using AKT2 Antibody.
Application
Immunohistochemistry staining of AKT2 in kidney using AKT2 Antibody.| Application Notes | AKT2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store AKT2 antibody at 4 ˚C, Avoid Freezing |
| Storage Buffer | PBS, 0.05% sodium azide. |
