| Product Name | PSMA antibody [Y/PSMA1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [Y/PSMA1] to PSMAThis gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | Y/PSMA1 |
| Host Species | Mouse |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FGCP, FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA, mGCP |
|---|---|
| Target | PSMA |
| Tissue Specificity | Prostate Specific Membrane Antigen (PSMA) |
| Light Chain Type | kappa |
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at –20°C. Avoid multiple freeze/thaw cycles. |
| Storage Buffer | Lyophilized from 0.01M PBS, pH 7.0 |
