Mouse monoclonal [PTY10] to PTP1CPlays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.
Immunogen
Recombinant full length protein (Human).
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
PTY10
Host Species
Mouse
Tested Applications
ICC/IFIPWB
ICC/IF:1:200~1:500 IP:1:100~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)