Mouse monoclonal [PTY6] to PTP1CPlays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.
Immunogen
Recombinant human full length protein
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
PTY6
Host Species
Mouse
Tested Applications
ICC/IFIPWB
For ICC: Use at an assay dependent dilution. For IP: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
This antibody recognizes the SH2(C) domain of the 67 kDa PTP1C
Light Chain Type
kappa
Application Notes
For ICC: Use at an assay dependent dilution. For IP: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.:
Additional Information
Form
Liquid
Storage Instructions
Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Storage Buffer
0.01M Phosphate-buffered saline, pH 7.2, containing no preservatives