| Product Name | CD16 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR-10, FCRIII, FCGRIII, FCRIIIA, FCGR3A |
| Product description | The CB15 monoclonal antibody specifically binds to human CD16, a low affinity Fc receptor. It is expressed on NK, neutrophils, macrophages, monocytes, and placental trophoblasts. CD16 is expressed in CD16a and CD16b forms. CD16a is a polyeptide anchored transmembrane protein and CD16b is a monomeric glycosylphosphatidylinositol (GPI)-anchored protein found in neutrophils. CD16 is reported to be involved in NK cell activation and signal transduction.1) Deaglio, S., Zubiaur, M., Gregorini, A., Bottarel, F., Ausiello, C. M., Dianzani, U., ... Malavasi, F. (2002). Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells.Blood,99(7), 2490-2498. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | FACSFunctionalStudies |
| FACS:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FCGR3A |
|---|---|
| Alternative Names | CD16 FCG3 CD16A FCGR3 IGFR3 IMD20 FCR-10 FCRIII FCGRIII FCRIIIA FCGR3A |
| Tissue Specificity | The CB15 monoclonal antibody specifically binds to human CD16, a low affinity Fc receptor. |
| Entrez Gene | 2214 |
|---|
| Application Notes | FACS:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The product should be stored undiluted at 4˚C . Do not freeze. |
| Storage Buffer | Phosphate-buffered aqueous solution, ph7.2. |
