The antibody 4H11[APG] reacts with Class III epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells.
Immunogen
CD34 monoclonal antibody was raised against a permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia (Human).