Application
Immunohistochemistry staining of CXCR4 in brain cortex tissue using CXCR4 monoclonal Antibody.| Product Name | CXCR4 Antibody [12G5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | FACSIFIHC |
| CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL. | |
| Species Reactivity | BaboonChimpanzeeHumanMonkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CXCR4 |
|---|---|
| Alternative Names | CXCR4 CD184 CD184 antigen Cmkar4 Cxc chemokine receptor 4 CXCR-4 CXC-R4 D2S201E FB22 Fusin HM89 LCR1 NPY3R NPYRL NPYY3R Npyy3 HSY3RR SDF-1 receptor WHIM C-x-c chemokine receptor 4 LESTR Neuropeptide Y receptor Y3 NPYR |
Application
Immunohistochemistry staining of CXCR4 in brain cortex tissue using CXCR4 monoclonal Antibody.| Application Notes | CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store CXCR4 antibody at 4 ˚C, Avoid Freezing |
| Storage Buffer | PBS, pH 7.2, 0.09% sodium azide. |
