Application
Antibody used in WB on Human Hela at 1 ug/ml.Application
Antibody used in IHC on Human HK2.Application
Antibody used in WB on Hum. Fetal Liver at 1 ug/ml.Application
Antibody used in IHC on Human HK2.Application
Antibody used in WB on Human HeLa at 1 ug/ml.Application
Antibody used in IHC on Human HK2.Application
Antibody used in IHC on Human Placenta at 5.0 ug/ml.| Product Name | CYP11A1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11A1 localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.1) Shigematsu, K., (2008) Eur. J. Endocrinol. 158 (6), 867-878. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP11A1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| CYP11A1 antibody can be used for detection of CYP11A1 by ELISA at 1:1562500. CYP11A1 antibody can be used for detection of CYP11A1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CYP11A1 |
|---|---|
| Alternative Names | CYP11A1 CYP11A P450SCC CYPXIA1 |
| Molecular Weight(MW) | 57 kDa |
Application
Antibody used in WB on Human Hela at 1 ug/ml.
Application
Antibody used in IHC on Human HK2.
Application
Antibody used in WB on Hum. Fetal Liver at 1 ug/ml.
Application
Antibody used in IHC on Human HK2.
Application
Antibody used in WB on Human HeLa at 1 ug/ml.
Application
Antibody used in IHC on Human HK2.
Application
Antibody used in IHC on Human Placenta at 5.0 ug/ml.| Application Notes | CYP11A1 antibody can be used for detection of CYP11A1 by ELISA at 1:1562500. CYP11A1 antibody can be used for detection of CYP11A1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CYP11A1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
Data sheet for OM276551