CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones.1) Celhar,T., Cancer Genet. Cytogenet. 187 (1), 28-33 (2008)
Immunogen
This CYP11A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-120 amino acids from the N-terminal region of human CYP11A1.
Western blot analysis of anti-CYP11A1 Antibody in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.