Application
Immunohistochemistry staining of DDR1 in decidual cells using DDR1 Antibody.| Product Name | DDR1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DDR1, Cell adhesion kinase, CD167, CD167a antigen, EDDR1, ENTRK4, Mammary carcinoma kinase 10, MCK10, NEP, PTK3, PTK3A, RTK6, Tyrosine-protein kinase CAK, CAK, DDR, Discoidin domain receptor 1, HGK2, MCK-10, NTRK4, Protein-tyrosine kinase 3A, Protein-tyros |
| Product description | DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors. |
| Immunogen | DDR1 antibody was raised against a peptide located near the C-Terminal region of DDR1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| DDR1 antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunocytochemistry, immunohistochemistry starting at 10 μg/mL, immunoprecipitation starting at 1 - 2 μg/mL, and flow cytometry.: |
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| Species Reactivity | BatBovineChimpanzeeDogGibbonGorillaHorseHumanMonkeyPig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DDR1 |
|---|---|
| Alternative Names | DDR1 Cell adhesion kinase CD167 CD167a antigen EDDR1 ENTRK4 Mammary carcinoma kinase 10 MCK10 NEP PTK3 PTK3A RTK6 Tyrosine-protein kinase CAK CAK DDR Discoidin domain receptor 1 HGK2 MCK-10 NTRK4 Protein-tyrosine kinase 3A Protein-tyros |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDR2 (69%). |
Application
Immunohistochemistry staining of DDR1 in decidual cells using DDR1 Antibody.| Application Notes | DDR1 antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunocytochemistry, immunohistochemistry starting at 10 μg/mL, immunoprecipitation starting at 1 - 2 μg/mL, and flow cytometry.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | DDR1 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
