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MAPK11 Antibody
Catalog Number:OM284147
OM284147
Discount Price
OM284147-100ul
1~2 Week
100ul
OM284147-50ul
50ul
OM284147-20ul
20ul
1~2 Week
Product Profile
Product Name MAPK11 Antibody
Antibody Type Primary Antibodies
Product description MAPK11 is a Ser/Thr kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. It preferentially phosphorylates transcription factor ATF2. This protein is activated by phosphorylation on threonine and tyrosine by MKK6, and is inhibited by pyridinyl-imidazole related compounds. Highest expression levels are in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.1) Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Immunogen This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-366 amino acids from the center region of human MAPK11.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Unpurified
Target Information
Gene Symbol MAPK11
Alternative Names Mitogen-activated protein kinase 11
MAP kinase 11
MAPK 11
Mitogen-activated protein kinase p38 beta
MAP kinase p38 beta
p38b
Stress-activated protein kinase 2b
SAPK2b
p38-2
MAPK11
PRKM11
SAPK2
SAPK2B
Molecular Weight(MW) 41 kDa
Database Links
Entrez Gene 5600
Protein Accession Q15759
Application

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.

Application

Western blot analysis of anti-MAPK11 Pab in mouse brain tissue lysate
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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